The primary objective of the study was to determine the effect of EGb761 in treatment on the rate of conversion from memory complaints to Alzheimer’s disease using survival analysis.
The main targets for this study were ambulatory patients aged 70 years who exhibited memory complaints during a GP or memory centre consultation. Those with objective memory impairment or clinically relevant symptoms of anxiety and depression were however excluded. Participants were then required to make annual visits to a memory center where a series of neuropsychological tests were conducted to assess the cognitive function and cognitive status. The functional status was evaluated with the Instrumental Activities of Daily Living Questionnaire (Andrieu et. al., 2008, p.406).
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