Sample Essay
The second researched (Rocca et al., 1998 &Sacerdote et al., 1999) on approach in the underlying neurological mechanisms for GAD and depression is the study of the benzodiazepine receptors. Since, in GAD patients numbers of peripheral benzodiazepine receptor-binding sites in lymphocyte membranes show a reduction by 45 percent than the normal persons. Thus this observation indicates that dysregulation of peripheral benzodiazepine receptors offers a possible mechanism in Generalized Anxiety Disorder.
Thirdly, the study of the serotonin (5-HT) system study is also one of the most current developments in GAD research in relation to unfolding its neurological mechanism. In this study 5-HT level is examined in patients with GAD. In regard to 5-HT, (George and Price, 1994) states that 5-HT is used not only because it is widely distributed throughout the brain particularly, but also these distributed regions deal or are associated with anxiety which we are interested in. observation in GAD patients shows that 5-HT levels in the CSF (cerebrospinal fluid) are highly reduced as opposed to patients with depression have normal concentrations of 5-HT in the cerebrospinal fluid with an exception of suicidal patients who indicate reduced levels.
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